More than 720 libraries around the world have chosen to include participation in Portico as one important component of their digital preservation strategy. Early participants are designated Archive Founders and are identified as such in the lists below.
| Libraries | Archive Founders |
|---|---|
| Earlham College | yes |
| East Carolina University | yes |
| Eastern Michigan University | yes |
| Ecole de Technologie Superieure | yes |
| Edinburgh College of Art | |
| Edinburgh Napier University | |
| Elon University | yes |
| Embry-Riddle Aeronautical University | |
| Emporia State University | yes |
| Empresa Brasileira de Pesquisa Agropecuária | |
| Ente per le Nuove tecnologie, l'Energia e l'Ambiente (ENEA) (National Agency for New Technologies, Energy and the Environment) | yes |
| Erskine College and Seminary | yes |
| Escola Nacional de Ciências Estatísticas | |
| Escola Superior de Teologia | |
| European University Institute | yes |